CH

Chaidiscovery

Security Engineer

Salary Not Disclosed
San Francisco office

About Chai Discovery

Chai is a research lab working on generative models for molecular design. We are building AI infrastructure to engineer new medicines with speed and precision. The world’s largest pharmaceutical companies—including Eli Lilly, Pfizer, and Novartis—have started adopting our platform across their organizations.

Our mission is to unlock progress towards better cures and better science, and we see countless interesting problems on the road ahead. We are known for talent density, rigorous research and pace of execution.

Our founders have been at the forefront of this field from the beginning. We are backed by Sequoia, Index, Thrive, General Catalyst, Dimension, OpenAI and others.

About the role

Security is what earns Chai the trust of the world's largest pharma companies. It's a precondition for the business. We're looking for someone to help own and build the security function end to end.

You'll represent Chai's security posture to our partners, sitting across from their CISOs and cloud security architects on reviews of our compute architecture, tenant isolation, egress controls, encryption, and key management. You'll drive the changes they surface back into our platform and infrastructure, keeping Chai ahead of new risks.

Just as importantly, you'll be the trusted security partner to our product and platform engineers, reviewing systems like our shared inference fleets and per-partner data isolation before they're built, shipping security controls that are tricky for non-specialists to get right, while automating compliance, onboarding, and vendor work so the program mostly runs itself.

Our models have moved beyond structure prediction into real therapeutic engineering, and the partnerships that come with that raise the bar every quarter.

About you

We index on judgment, breadth, and the instinct to build security in rather than bolt it on. The archetype is an engineer who specialized into security, thinks about the business as much as the threat model, and would rather partner with engineers than audit them. We look for:

  • 5+ years in security engineering, having built or meaningfully improved a security program at a high-growth company -- you have intuition for what a 30-person startup needs versus a 1,000-person one

  • ability to write targeted production code in python and typescript, not just scripts

  • startup or high-growth experience, working close to engineering rather than at arm's length

  • credibility and presence to represent Chai on calls with pharma CISOs

  • comfort owning detection, response, and incident management end to end

  • familiarity with SOC 2 and ISO 27001 as programs to run well, not boxes to check

Life sciences or other regulated-industry experience is a bonus. A background in biology is not required. What makes the difference is technical excellence, business sense, and grit.

We offer

The opportunity to work at the leading edge of AI research, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We offer highly competitive compensation.

Be cautious! Do not send money to a potential employer. Do not pay any money for a potential contract of employment or for pre-employment training.

Job Summary

About Chai Discovery Chai is a research lab working on generative models for molecular design. We are building AI infrastructure to engineer new medicines with speed and precision. The world’s largest pharmaceutical companies—including Eli Lilly, Pfizer, and Novartis—have starte

Application DeadlineSaturday, August 1st, 2026
Salary
Not Disclosed
Job TypeFull Time
Experience LevelMid Level
Experience Length2 years
Date PostedSaturday, July 18th, 2026

Share this job